Epidermal Growth Factor Pathway Signaling in Drosophila Embryogenesis: Tools for Understanding Cancer

Epidermal Growth Factor Pathway Signaling in Drosophila Embryogenesis: Tools for Understanding Cancer

EGF signaling is a well-known oncogenic pathway in animals. It is also a key developmental pathway regulating terminal and dorsal-ventral patterning along with many other aspects of embryogenesis. In this review, we focus on the diverse roles for the EGF pathway in Drosophila embryogenesis. We revie...

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Bibliographic Details
Main Authors: Jay B. Lusk, Vanessa Y. M. Lam, Nicholas S. Tolwinski
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:Cancers
Subjects:
EGF signaling
Drosophila development
RAS
RAF
MAP kinase
MEK
Online Access:http://www.mdpi.com/2072-6694/9/2/16

Internet

http://www.mdpi.com/2072-6694/9/2/16

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