Regulation of oxytocin-induced calcium transients and gene expression in engineered myometrial tissues by tissue architecture and matrix rigidity

The uterus is susceptible to benign tumors known as fibroids, which have been associated with many pregnancy complications, including preterm labor. However, the impact of fibrotic tissue remodeling on the physiology of the myometrium, the smooth muscle layer of the uterus, is poorly understood, in...

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Bibliographic Details
Main Authors: Antonina P. Maxey, Jaya M. Travis, Megan L. McCain
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Physiology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944123000111