Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases

Safety of Anti-Reelin Therapeutic Approaches for Chronic Inflammatory Diseases

Reelin, a large extracellular glycoprotein, plays critical roles in neuronal development and synaptic plasticity in the central nervous system (CNS). Recent studies have revealed non-neuronal functions of plasma Reelin in inflammation by promoting endothelial–leukocyte adhesion through its canonical...

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Bibliographic Details
Main Authors: Laurent Calvier, Anna Alexander, Austin T. Marckx, Maria Z. Kounnas, Murat Durakoglugil, Joachim Herz
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:Cells
Subjects:
Reelin
ApoER2
NF-κB
vascular system
immune system
fibrosis
Online Access:https://www.mdpi.com/2073-4409/13/7/583

Internet

https://www.mdpi.com/2073-4409/13/7/583

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