Crosstalk of Synapsin1 palmitoylation and phosphorylation controls the dynamicity of synaptic vesicles in neurons

Crosstalk of Synapsin1 palmitoylation and phosphorylation controls the dynamicity of synaptic vesicles in neurons

Abstract The dynamics of synaptic vesicles (SVs) within presynaptic domains are tightly controlled by synapsin1 phosphorylation; however, the mechanism underlying the anchoring of synapsin1 with F-actin or SVs is not yet fully understood. Here, we found that Syn1 is modified with protein palmitoylat...

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Bibliographic Details
Main Authors: Peipei Yan, Huicong Liu, Tao Zhou, Pu Sun, Yilin Wang, Xibin Wang, Lin Zhang, Tian Wang, Jing Dong, Jiangli Zhu, Luxian Lv, Wenqiang Li, Shiqian Qi, Yinming Liang, Eryan Kong
Format: Article
Language:English
Published: Nature Publishing Group 2022-09-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-022-05235-4

Internet

https://doi.org/10.1038/s41419-022-05235-4

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