A computational approach based on weighted gene co-expression network analysis for biomarkers analysis of Parkinson’s disease and construction of diagnostic model

A computational approach based on weighted gene co-expression network analysis for biomarkers analysis of Parkinson’s disease and construction of diagnostic model

BackgroundParkinson’s disease (PD) is a common age-related chronic neurodegenerative disease. There is currently no affordable, effective, and less invasive test for PD diagnosis. Metabolite profiling in blood and blood-based gene transcripts is thought to be an ideal method for diagnosing PD.AimIn...

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Bibliographic Details
Main Authors: Zhaoping Wu, Zhiping Hu, Yunchun Gao, Yuechong Xia, Xiaobo Zhang, Zheng Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Computational Neuroscience
Subjects:
Parkinson’s disease
WGCNA
LASSO regression
potential diagnostic predictor
computational approach
Online Access:https://www.frontiersin.org/articles/10.3389/fncom.2022.1095676/full

Internet

https://www.frontiersin.org/articles/10.3389/fncom.2022.1095676/full

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