Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin

Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin

Summary: The differentiation of embryonic stem cells (ESCs) begins with the transition from the naive to the primed state. The formative state was recently established as a critical intermediate between the two states. Here, we demonstrate the role of the histone chaperone FACT in regulating the nai...

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Bibliographic Details
Main Authors: Hang Zhao, Di Li, Xue Xiao, Cuifang Liu, Guifang Chen, Xiaoyu Su, Zhenxin Yan, Shijia Gu, Yizhou Wang, Guohong Li, Jianxun Feng, Wei Li, Ping Chen, Jiayi Yang, Qing Li
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:iScience
Subjects:
Molecular biology
Epigenetics
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223026147

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http://www.sciencedirect.com/science/article/pii/S2589004223026147

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