Efficacy and Side Effects of Natalizumab Therapy in Patients with Multiple Sclerosis
Natalizumab (Nat) is a humanized monoclonal antibody used for the treatment of relapsing multiple sclerosis (MS). Nat inhibits lymphocyte migration via the blood brain barrier (BBB) by blockage of an integrin adhesion molecule, very late antigen 4. During the phase III clinical trials, it was shown...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2014-01-01
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| Series: | Journal of Central Nervous System Disease |
| Online Access: | https://doi.org/10.4137/JCNSD.S14049 |