The Effect of Selective Endothelin Receptor a Antagonism by Bq-123 on Myocardial Ischemia-Reperfusion Induced Apoptotic Cell Death

The Effect of Selective Endothelin Receptor a Antagonism by Bq-123 on Myocardial Ischemia-Reperfusion Induced Apoptotic Cell Death

The objective of the present study was to investigate the possible impact of specific endothelin-A (ETA) receptor blockage by BQ-123 on myocardial ischemia-reperfusion (MI/R) induced apoptosis in rats. To produce MI/R, a branch of the descending left coronary artery was occluded for 30 min followed...

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Detalles Bibliográficos
Main Authors: Mehmet Cengiz Colak, Hakan Parlakpinar, Necip Ermis, Alaadin Polat, Cemil Colak, Bulent Mizrak, Ramazan Ozdemir, Ahmet Acet
Formato: Artigo
Idioma:English
Publicado: Society of Turaz Bilim 2012-12-01
Series:Medicine Science
Subjects:
Apoptosis
ETA receptor antagonist (BQ-123)
endothelin; NO
reactive oxygen radicals
rat
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