Didang Tang inhibits intracerebral hemorrhage-induced neuronal injury via ASK1/MKK7/JNK signaling pathway, network pharmacology-based analyses combined with experimental validation

Didang Tang inhibits intracerebral hemorrhage-induced neuronal injury via ASK1/MKK7/JNK signaling pathway, network pharmacology-based analyses combined with experimental validation

Background: Intracerebral hemorrhage (ICH) is an acute cerebrovascular disease, which is also a principal consideration for disability. Didang tang (DDT) is a classic traditional Chinese medicine formula for treating ICH. However, its pharmacological mechanism of action has not been elucidated. Mate...

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Bibliographic Details
Main Authors: Jing Lu, Xiaolei Tang, Dongmei Zhang, Tianye Lan, Qingxia Huang, Peng Xu, Miao Liu, Li Liu, Jian Wang
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Heliyon
Subjects:
Intracerebral hemorrhage
Didang tang
ASK1/MKK7/JNK
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022026950

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http://www.sciencedirect.com/science/article/pii/S2405844022026950

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