Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs.

Bayesian mixed model analysis uncovered 21 risk loci for chronic kidney disease in boxer dogs.

Chronic kidney disease (CKD) affects 10% of the human population, with only a small fraction genetically defined. CKD is also common in dogs and has been diagnosed in nearly all breeds, but its genetic basis remains unclear. Here, we performed a Bayesian mixed model genome-wide association analysis...

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Bibliographic Details
Main Authors: Frode Lingaas, Katarina Tengvall, Johan Høgset Jansen, Lena Pelander, Maria H Hurst, Theo Meuwissen, Åsa Karlsson, Jennifer R S Meadows, Elisabeth Sundström, Stein Istre Thoresen, Ellen Frøysadal Arnet, Ole Albert Guttersrud, Marcin Kierczak, Marjo K Hytönen, Hannes Lohi, Åke Hedhammar, Kerstin Lindblad-Toh, Chao Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010599

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https://doi.org/10.1371/journal.pgen.1010599

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