The genomic signature of resistance to platinum-containing neoadjuvant therapy based on single-cell data

The genomic signature of resistance to platinum-containing neoadjuvant therapy based on single-cell data

Abstract Background Neoadjuvant chemotherapy (NACT) becomes the first-line option for advanced tumors, while patients who are not sensitive to it may not benefit. Therefore, it is important to screen patients suitable for NACT. Methods Single-cell data of lung adenocarcinoma (LUAD) and esophageal sq...

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Bibliographic Details
Main Authors: Qihai Sui, Zhengyang Hu, Xing Jin, Yunyi Bian, Jiaqi Liang, Huan Zhang, Huiqiang Yang, Zongwu Lin, Qun Wang, Cheng Zhan, Zhencong Chen
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell & Bioscience
Subjects:
Neoadjuvant chemotherapy (NACT)
Cisplatin (CDDP)
Single-cell analysis
Gene expression
Drug resistance
Online Access:https://doi.org/10.1186/s13578-023-01061-z

Internet

https://doi.org/10.1186/s13578-023-01061-z

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