p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin

p62-Nrf2 Regulatory Loop Mediates the Anti-Pulmonary Fibrosis Effect of Bergenin

Idiopathic pulmonary fibrosis (IPF) can severely disrupt lung function, leading to fatal consequences, and there is currently a lack of specific therapeutic drugs. Bergenin is an isocoumarin compound with lots of biological functions including antioxidant activity. This study evaluated the potential...

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Bibliographic Details
Main Authors: Qian Zeng, Tingting Zhou, Feiyan Zhao, Dayan Xiong, Bin He, Qingzhong Hua, Miao Lin, Lang Deng, Xiaoxue Sang, Weixi Xie, Jia Chen, Zun Wang, Lu Ren, Ziqiang Luo, Xiaoting Huang, Wei Liu, Siyuan Tang
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Antioxidants
Subjects:
bergenin
oxidative stress
nuclear factor erythroid 2-related factor 2
p62/SQSTM1
idiopathic pulmonary fibrosis
myofibroblast
Online Access:https://www.mdpi.com/2076-3921/11/2/307

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https://www.mdpi.com/2076-3921/11/2/307

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