Association of IGFBP3 Gene (rs2854744) Polymorphism and Colorectal Cancer

BACKGROUND AND OBJECTIVE: The bioavailability of IGF1 is regulated by the insulin-like growth factor binding protein 3 (IGFBP3). IGFBP3 is an inhibitor of IGF1 and inhibits growth cell and induces apoptosis by joining to it. Some studies have shown that reduction of IGFBP3 level cause to increase ri...

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Bibliographic Details
Main Authors: M Arkani, KH Karimi, A Safaei, M Vahedi, SR Mohebi, SR Fatemi, M Vafaei, MR Zali
Format: Article
Language:English
Published: Babol University of Medical Sciences 2012-05-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Subjects:
Online Access:http://jbums.org/article-1-4089-en.html