Transposon-Based CAR T Cells in Acute Leukemias: Where Are We Going?

Chimeric Antigen Receptor (CAR) T-cell therapy has become a new therapeutic reality for refractory and relapsed leukemia patients and is also emerging as a potential therapeutic option in solid tumors. Viral vector-based CAR T-cells initially drove these successful efforts; however, high costs and c...

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Bibliographic Details
Main Authors: Chiara F. Magnani, Sarah Tettamanti, Gaia Alberti, Ilaria Pisani, Andrea Biondi, Marta Serafini, Giuseppe Gaipa
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/6/1337