[11C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years

[11C]Carbon monoxide: advances in production and application to PET radiotracer development over the past 15 years

Abstract [11C]Carbon monoxide is an appealing synthon for introducing carbon-11 at a carbonyl position (C=O) in a wide variety of chemotypes (e.g., amides, ketones, acids, esters, and ureas). The prevalence of the carbonyl group in drug molecules and the present-day broad versatility of carbonylatio...

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Bibliographic Details
Main Authors: Carlotta Taddei, Victor W. Pike
Format: Article
Language:English
Published: SpringerOpen 2019-09-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Carbon-11
PET
Carbon monoxide
Radiochemistry
Carbonylation
Radiotracer
Online Access:http://link.springer.com/article/10.1186/s41181-019-0073-4

Internet

http://link.springer.com/article/10.1186/s41181-019-0073-4

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