Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives

Design, Synthesis, and Antipoliferative Activities of Novel Substituted Imidazole-Thione Linked Benzotriazole Derivatives

A new series of benzotriazole moiety bearing substituted imidazol-2-thiones at N1 has been designed, synthesized and evaluated for in vitro anticancer activity against the different cancer cell lines MCF-7(breast cancer), HL-60 (Human promyelocytic leukemia), and HCT-116 (colon cancer). Most of the...

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Bibliographic Details
Main Authors: Ahdab N. Khayyat, Khaled O. Mohamed, Azizah M. Malebari, Afaf El-Malah
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Molecules
Subjects:
benzotriazole
anticancer
imidazol-2-thione
antiproliferative activity
breast cancer
colchicine
Online Access:https://www.mdpi.com/1420-3049/26/19/5983

Internet

https://www.mdpi.com/1420-3049/26/19/5983

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