Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.

Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shear.

The generation of thrombin is a critical process in the formation of venous thrombi. In isolated plasma under static conditions, phosphatidylserine (PS)-exposing platelets support coagulation factor activation and thrombin generation; however, their role in supporting coagulation factor binding unde...

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Bibliographic Details
Main Authors: Michelle A Berny, Imke C A Munnix, Jocelyn M Auger, Saskia E M Schols, Judith M E M Cosemans, Peter Panizzi, Paul E Bock, Steve P Watson, Owen J T McCarty, Johan W M Heemskerk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2861630?pdf=render

Internet

http://europepmc.org/articles/PMC2861630?pdf=render

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