A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy

A Network Medicine Approach for Drug Repurposing in Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is a progressive hereditary muscular disease caused by a lack of dystrophin, leading to membrane instability, cell damage, and inflammatory response. However, gene-editing alone is not enough to restore the healthy phenotype and additional treatments are required. I...

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Bibliographic Details
Main Authors: Salvo Danilo Lombardo, Maria Sofia Basile, Rosella Ciurleo, Alessia Bramanti, Antonio Arcidiacono, Katia Mangano, Placido Bramanti, Ferdinando Nicoletti, Paolo Fagone
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
Duchenne muscular dystrophy
microarray analysis
network medicine
protein–protein interactions
drug discovery
drug repurposing
Online Access:https://www.mdpi.com/2073-4425/12/4/543

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https://www.mdpi.com/2073-4425/12/4/543

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