Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2

Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2

Glycosylation inhibition has great potential in cancer treatment. However, the corresponding cellular response, protein expression and glycosylation changes remain unclear. As a cell-permeable small-molecule inhibitor with reduced cellular toxicity, N-linked glycosylation inhibitor-1 (NGI-1) has bec...

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Bibliographic Details
Main Authors: Xinyi Cao, Peiyi Meng, Yuyin Shao, Guoquan Yan, Jun Yao, Xinwen Zhou, Chao Liu, Lei Zhang, Hong Shu, Haojie Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Molecular Biosciences
Subjects:
hepatocellular carcinoma
nascent proteome
glycosylation
glycoproteome
LAMP2
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.899192/full

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https://www.frontiersin.org/articles/10.3389/fmolb.2022.899192/full

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