The <it>l</it><sub>1</sub>-<it>l</it><sub>2 </sub>regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines

<p>Abstract</p> <p>Background</p> <p>Gene expression signatures are clusters of genes discriminating different statuses of the cells and their definition is critical for understanding the molecular bases of diseases. The identification of a gene signature is complicated...

Full description

Bibliographic Details
Main Authors: Rosasco Lorenzo, Mosci Sofia, Barla Annalisa, Fardin Paolo, Verri Alessandro, Varesio Luigi
Format: Article
Language:English
Published: BMC 2009-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/10/474