The <it>l</it><sub>1</sub>-<it>l</it><sub>2 </sub>regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines
<p>Abstract</p> <p>Background</p> <p>Gene expression signatures are clusters of genes discriminating different statuses of the cells and their definition is critical for understanding the molecular bases of diseases. The identification of a gene signature is complicated...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-10-01
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Series: | BMC Genomics |
Online Access: | http://www.biomedcentral.com/1471-2164/10/474 |