A deep learning approach to real-time Markov modeling of ion channel gating
Abstract The patch-clamp technique allows us to eavesdrop the gating behavior of individual ion channels with unprecedented temporal resolution. The signals arise from conformational changes of the channel protein as it makes rapid transitions between conducting and non-conducting states. However, u...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-11-01
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Series: | Communications Chemistry |
Online Access: | https://doi.org/10.1038/s42004-024-01369-y |