BRAF mutation and its inhibitors in sarcoma treatment
Abstract The mitogen‐activated protein kinase (MAPK) signaling pathway plays a significant role in mediating cellular physiological activities, such as proliferation, differentiation, apoptosis, and senescence. This signaling pathway is composed of several major proto‐oncogenes of RAS/RAF/MEK/ERK, a...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
Wiley
2020-07-01
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Series: | Cancer Medicine |
Subjects: | |
Online Access: | https://doi.org/10.1002/cam4.3103 |