BRAF mutation and its inhibitors in sarcoma treatment

Abstract The mitogen‐activated protein kinase (MAPK) signaling pathway plays a significant role in mediating cellular physiological activities, such as proliferation, differentiation, apoptosis, and senescence. This signaling pathway is composed of several major proto‐oncogenes of RAS/RAF/MEK/ERK, a...

Full description

Bibliographic Details
Main Authors: Haotian Liu, Nahar Nazmun, Shafat Hassan, Xinyue Liu, Jilong Yang
Format: Article
Language:English
Published: Wiley 2020-07-01
Series:Cancer Medicine
Subjects:
Online Access:https://doi.org/10.1002/cam4.3103