Transcriptome analysis of cardiac endothelial cells after myocardial infarction reveals temporal changes and long-term deficits

Abstract Endothelial cells (ECs) have essential roles in cardiac tissue repair after myocardial infarction (MI). To establish stage-specific and long-term effects of the ischemic injury on cardiac ECs, we analyzed their transcriptome at landmark time points after MI in mice. We found that early EC r...

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Bibliographic Details
Main Authors: Chitra Basu, Presley L. Cannon, Cassandra P. Awgulewitsch, Cristi L. Galindo, Eric R. Gamazon, Antonis K. Hatzopoulos
Format: Article
Language:English
Published: Nature Portfolio 2024-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-59155-8