Commensal bacteria signal through TLR5 and AhR to improve barrier integrity and prevent allergic responses to food

Summary: The increasing prevalence of food allergies has been linked to reduced commensal microbial diversity. In this article, we describe two features of allergy-protective Clostridia that contribute to their beneficial effects. Some Clostridial taxa bear flagella (a ligand for TLR5) and produce i...

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Bibliographic Details
Main Authors: Andrea M. Kemter, Robert T. Patry, Jack Arnold, Lauren A. Hesser, Evelyn Campbell, Edward Ionescu, Mark Mimee, Shan Wang, Cathryn R. Nagler
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011658