Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis

Antibody-Mediated LILRB2-Receptor Antagonism Induces Human Myeloid-Derived Suppressor Cells to Kill Mycobacterium tuberculosis

Tuberculosis is a leading cause of death in mankind due to infectious agents, and Mycobacterium tuberculosis (Mtb) infects and survives in macrophages (MФs). Although MФs are a major niche, myeloid-derived suppressor cells (MDSCs) are an alternative site for pathogen persistence. Both MФs and MDSCs...

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Bibliografski detalji
Glavni autori: Vipul K. Singh, Arshad Khan, Yitian Xu, Sunny Mai, Licheng Zhang, Abhishek Mishra, Blanca I. Restrepo, Ping-Ying Pan, Shu-Hsia Chen, Chinnaswamy Jagannath
Format: Članak
Jezik:English
Izdano: Frontiers Media S.A. 2022-06-01
Serija:Frontiers in Immunology
Teme:
tuberculosis
MDSC (myeloid-derived suppressor cell)
LILRB
monoclonal antibody
Mycobacterium
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2022.865503/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.865503/full

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