Peripheral effects of FAAH deficiency on fuel and energy homeostasis: role of dysregulated lysine acetylation.

FAAH (fatty acid amide hydrolase), primarily expressed in the liver, hydrolyzes the endocannabinoids fatty acid ethanolamides (FAA). Human FAAH gene mutations are associated with increased body weight and obesity. In our present study, using targeted metabolite and lipid profiling, and new global ac...

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Bibliographic Details
Main Authors: Bhavapriya Vaitheesvaran, Li Yang, Kirsten Hartil, Sherrye Glaser, Stephen Yazulla, James E Bruce, Irwin J Kurland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3307749?pdf=render