Structural Study of the Complex of <i>cblC</i> Methylmalonic Aciduria and Homocystinuria-Related Protein MMACHC with Cyanocobalamin

Structural Study of the Complex of <i>cblC</i> Methylmalonic Aciduria and Homocystinuria-Related Protein MMACHC with Cyanocobalamin

MMACHC is an essential protein for the body to metabolise vitamin B<sub>12</sub>, and its deficiency will cause <i>cblC</i>-type methylmalonic aciduria and homocystinuria. MMACHC can interact with cyanocobalamin (a type of vitamin B<sub>12</sub>) cofactor and play...

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Bibliographic Details
Main Authors: Qin Xu, Huan Zhou, Minjun Li, Weiwei Wang, Mengxue Xu, Zhimin Zhu, Chenyu Zhang, Qisheng Wang, Feng Yu, Jianhua He
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Crystals
Subjects:
MMACHC
cyanocobalamin
vitamin B<sub>12</sub>
complex structure
X-ray diffraction
Online Access:https://www.mdpi.com/2073-4352/12/4/468

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https://www.mdpi.com/2073-4352/12/4/468

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