OLFM2 promotes epithelial-mesenchymal transition, migration, and invasion in colorectal cancer through the TGF-β/Smad signaling pathway

OLFM2 promotes epithelial-mesenchymal transition, migration, and invasion in colorectal cancer through the TGF-β/Smad signaling pathway

Abstract Background Colorectal cancer (CRC) is an aggressive tumor of the gastrointestinal tract, which is a major public health concern worldwide. Despite numerous studies, the precise mechanism of metastasis behind its progression remains elusive. As a member of the containing olfactomedin domains...

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Bibliographic Details
Main Authors: Yong Tang, Yi Liu, Xiaobo Wang, Haiyang Guo, Lin Chen, Guangbing Hu, Yutong Cui, Shiqi Liang, Ji Zuo, Zichen Luo, Xinrui Chen, Xianfei Wang
Format: Article
Language:English
Published: BMC 2024-02-01
Series:BMC Cancer
Subjects:
OLFM2
EMT
TGF-β/Smad signaling pathway
Colorectal cancer
Online Access:https://doi.org/10.1186/s12885-024-11925-3

Internet

https://doi.org/10.1186/s12885-024-11925-3

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