Use of poxvirus display to select antibodies specific for complex membrane antigens

Use of poxvirus display to select antibodies specific for complex membrane antigens

ABSTRACTAntibody discovery against complex antigens is limited by the availability of a reproducible pure source of concentrated properly folded antigen. We have developed a technology to enable direct incorporation of membrane proteins such as GPCRs and into the membrane of poxvirus. The protein of...

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Bibliographic Details
Main Authors: Ernest S. Smith, Leslie A. Balch, Maria Scrivens, Shuying Shi, Wei Wang, Caroline D. Harvey, Angelica A. Cornelison, Malgorzata Gil-Moore, Renee A. Kirk, Loretta L. Mueller, Richard L. Hall, Alan P. Howell, Christine A. Reilly, Jessica M. Mayer, Francis G. Murante, Kari A Viggiani, Elaine M. Gersz, Holm Bussler, Madeleine R. Keefe, Elizabeth E. Evans, Mark J. Paris, Maurice Zauderer
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:mAbs
Subjects:
Antibody
GPCR
ion channel
membrane
panning
phage
Online Access:https://www.tandfonline.com/doi/10.1080/19420862.2023.2249947

Internet

https://www.tandfonline.com/doi/10.1080/19420862.2023.2249947

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