Rapid Identification of Coumarins from Micromelum falcatum by UPLC-HRMS/MS and Targeted Isolation of Three New Derivatives

Rapid Identification of Coumarins from Micromelum falcatum by UPLC-HRMS/MS and Targeted Isolation of Three New Derivatives

Micromelum falcatum, a medicinal plant of the Rutaceae family, has been used in the Traditional Chinese Medicine (TCM) mainly against colds and rheumatoid arthritis. Despite its traditional use the association of its constituents with possible anti-inflammatory activity has not been explored. During...

Full description

Bibliographic Details
Main Authors: Eirini Kouloura, Eirini Danika, Sothea Kim, Mélanie Hoerlé, Muriel Cuendet, Maria Halabalaki, Leandros A. Skaltsounis
Format: Article
Language:English
Published: MDPI AG 2014-09-01
Series:Molecules
Subjects:
Micromelum falcatum
Rutaceae
7-oxygenated coumarins
LC-MS
LTQ-Orbitrap
microfalcrin
microcoumaririn
micromelosidester
anti-inflammatory activity
NF-κB
NO production
Online Access:http://www.mdpi.com/1420-3049/19/9/15042

Internet

http://www.mdpi.com/1420-3049/19/9/15042

Similar Items