MicroRNA Let-7i Is a Promising Serum Biomarker for Post-stroke Cognitive Impairment and Alleviated OGD-Induced Cell Damage in vitro by Regulating Bcl-2

MicroRNA Let-7i Is a Promising Serum Biomarker for Post-stroke Cognitive Impairment and Alleviated OGD-Induced Cell Damage in vitro by Regulating Bcl-2

BackgroundThe mechanism of post-stroke cognitive impairment (PSCI) has not been explained. We aimed to investigate whether miR-let-7i participates in the PSCI and illuminates its underlying role in oxygen–glucose deprivation (OGD)-induced cell apoptosis.MethodsBlood samples from 36 subjects with PSC...

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Bibliographic Details
Main Authors: Zhan-Qiang Wang, Kuo Li, Jie Huang, Tian-Tian Huo, Pei-Yuan Lv
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Neuroscience
Subjects:
miR-let-7i
microRNA
post-stroke cognitive impairment
Bcl-2
cell damage
oxygen–glucose deprivation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00215/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.00215/full

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