Urinary markers of nucleic acid oxidation and cancer in type 2 diabetes

Urinary markers of nucleic acid oxidation and cancer in type 2 diabetes

Aims/hypothesis: We investigated whether urinary markers of nucleic acid oxidation are associated with an increased risk of cancer in type 2 diabetes patients. Methods: Urine samples from 1381 newly diagnosed diabetes patients were assayed for the oxidatively modified guanine nucleosides 8-oxo-7,8-d...

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Bibliographic Details
Main Authors: Kasper Broedbaek, Volkert Siersma, Trine Henriksen, Allan Weimann, Morten Petersen, Jon T. Andersen, Espen Jimenez-Solem, Lars J. Hansen, Jan Erik Henriksen, Steen J. Bonnema, Niels de Fine Olivarius, Søren Friis, Henrik E. Poulsen
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Redox Biology
Subjects:
Type 2 diabetes
Cancer
RNA oxidation
DNA oxidation
8‐oxo‐7,8‐dihydro‐2′‐deoxyguanosine
8‐oxo‐7,8‐dihydroguanosine
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231714001220

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http://www.sciencedirect.com/science/article/pii/S2213231714001220

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