High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET<sub>A</sub>/ET<sub>B</sub> Receptor and mTOR Pathway

High Glucose-Induced Cardiomyocyte Damage Involves Interplay between Endothelin ET-1/ET<sub>A</sub>/ET<sub>B</sub> Receptor and mTOR Pathway

Patients with type two diabetes mellitus (T2DM) are at increased risk for cardiovascular diseases. Impairments of endothelin-1 (ET-1) signaling and mTOR pathway have been implicated in diabetic cardiomyopathies. However, the molecular interplay between the ET-1 and mTOR pathway under high glucose (H...

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Bibliographic Details
Main Authors: Sudhir Pandey, Corina T. Madreiter-Sokolowski, Supachoke Mangmool, Warisara Parichatikanond
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:International Journal of Molecular Sciences
Subjects:
high glucose
endothelin-1
ET<sub>A</sub>-R
ET<sub>B</sub>-R
mTOR
mitochondrial dysfunction
Online Access:https://www.mdpi.com/1422-0067/23/22/13816

Internet

https://www.mdpi.com/1422-0067/23/22/13816

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