Circulatory Inflammatory Mediators in the Prediction of Anti-Tuberculous Drug-Induced Liver Injury Using RUCAM for Causality Assessment

Circulatory Inflammatory Mediators in the Prediction of Anti-Tuberculous Drug-Induced Liver Injury Using RUCAM for Causality Assessment

Background: Anti-tuberculous (TB) medications are common causes of drug-induced liver injury (DILI). Limited data are available on systemic inflammatory mediators as biomarkers for predicting DILI before treatment. We aimed to select predictive markers among potential candidates and to formulate a p...

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Bibliographic Details
Main Authors: Cheng-Maw Ho, Chi-Ling Chen, Chia-Hao Chang, Meng-Rui Lee, Jann-Yuan Wang, Rey-Heng Hu, Po-Huang Lee
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Biomedicines
Subjects:
drug-induced liver injury
hepatotoxicity
inflammatory mediators
prediction model
tuberculosis
RUCAM (Roussel Uclaf Causality Assessment Method)
Online Access:https://www.mdpi.com/2227-9059/9/8/891

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https://www.mdpi.com/2227-9059/9/8/891

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