Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-κB and Nrf2/HO-1 Axes

Piceatannol SNEDDS Attenuates Estradiol-Induced Endometrial Hyperplasia in Rats by Modulation of NF-κB and Nrf2/HO-1 Axes

Endometrial hyperplasia (EH) is the most common risk factor for endometrial malignancy in females. The pathogenesis of EH has been directly linked to uterine inflammation, which can result in abnormal cell division and decreased apoptosis. Piceatannol (PIC), a natural polyphenolic stilbene, is known...

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Bibliographic Details
Main Authors: Lenah S. Binmahfouz, Basma G. Eid, Amina M. Bagher, Rasheed A. Shaik, Najlaa S. Binmahfouz, Ashraf B. Abdel-Naim
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Nutrients
Subjects:
estradiol benzoate
endometrial hyperplasia
oxidative stress
inflammation
piceatannol
Online Access:https://www.mdpi.com/2072-6643/14/9/1891

Internet

https://www.mdpi.com/2072-6643/14/9/1891

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