Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies

Relevance of Fc Gamma Receptor Polymorphisms in Cancer Therapy With Monoclonal Antibodies

Therapeutic monoclonal antibodies (mAbs), including immune checkpoint inhibitors (ICIs), are an important breakthrough for the treatment of cancer and have dramatically changed clinical outcomes in a wide variety of tumours. However, clinical response varies among patients receiving mAb-based treatm...

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Bibliographic Details
Main Authors: Juan J. Mata-Molanes, Joseba Rebollo-Liceaga, Elena Mª Martínez-Navarro, Ramón González Manzano, Antonio Brugarolas, Manel Juan, Manuel Sureda
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Oncology
Subjects:
cancer immunotherapy
Fc gamma receptor (FcγR)
immune checkpoint inhibitors
monoclonal Abs
polymorphisms
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.926289/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2022.926289/full

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