Modality diversification and best-in-class small-molecule drugs: Recent trend of orphan drug development

Only 5% of orphan diseases have approved drugs, leading to a high demand for new treatment. As a result, pharmaceutical companies have shifted their focus of drug development to orphan diseases. This study conducted a database search to analyze the modality and development strategy of orphan drugs a...

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Bibliographic Details
Main Author: Ryo Okuyama
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098623000064