Lipid-Associated GWAS Loci Predict Antiatherogenic Effects of Rosuvastatin in Patients with Coronary Artery Disease

Lipid-Associated GWAS Loci Predict Antiatherogenic Effects of Rosuvastatin in Patients with Coronary Artery Disease

We have shown that lipid-associated loci discovered by genome-wide association studies (GWAS) have pleiotropic effects on lipid metabolism, carotid intima-media thickness (CIMT), and CAD risk. Here, we investigated the impact of lipid-associated GWAS loci on the efficacy of rosuvastatin therapy in t...

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Bibliographic Details
Main Authors: Stanislav Kononov, Iuliia Azarova, Elena Klyosova, Marina Bykanova, Mikhail Churnosov, Maria Solodilova, Alexey Polonikov
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Genes
Subjects:
coronary artery disease
plasma lipids
carotid intima-media thickness
pharmacogenetics
personalized medicine
single nucleotide polymorphisms
Online Access:https://www.mdpi.com/2073-4425/14/6/1259

Internet

https://www.mdpi.com/2073-4425/14/6/1259

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