APRIL is overexpressed in cancer: link with tumor progression

<p>Abstract</p> <p>Background</p> <p>BAFF and APRIL share two receptors – TACI and BCMA – and BAFF binds to a third receptor, BAFF-R. Increased expression of BAFF and APRIL is noted in hematological malignancies. BAFF and APRIL are essential for the survival of normal a...

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Bibliographic Details
Main Authors: Veyrune Jean-Luc, Moreaux Jérôme, De Vos John, Klein Bernard
Format: Article
Language:English
Published: BMC 2009-03-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/9/83