Circ_0022920 Maintains the Contractile Phenotype of Human Aortic Vascular Smooth Muscle Cells Via Sponging microRNA‐650 and Promoting Transforming Growth Factor Beta Receptor 1 Expression in Angiotensin II‐Induced Models for Aortic Dissection

Circ_0022920 Maintains the Contractile Phenotype of Human Aortic Vascular Smooth Muscle Cells Via Sponging microRNA‐650 and Promoting Transforming Growth Factor Beta Receptor 1 Expression in Angiotensin II‐Induced Models for Aortic Dissection

Background Abnormal regulation of vascular smooth muscle cells is regarded as the iconic pathological change of aortic dissection (AD). Herein, we aim to identify circ_0022920 as a crucial regulator in AD. Methods and Results Microarray analysis of circular RNAs, messenger RNAs, and micro RNAs in pa...

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Bibliographic Details
Main Authors: Mao‐Xun Huang, Hu‐Lin Piao, Yong Wang, Zhi‐Cheng Zhu, Ri‐Hao Xu, Tian‐Ce Wang, Dan Li, Ke‐Xiang Liu
Format: Article
Language:English
Published: Wiley 2023-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
aortic dissection
Circ_0022920
contractile phenotype
miR‐650/IRF1/TGFβR1 axis
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.027425

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https://www.ahajournals.org/doi/10.1161/JAHA.122.027425

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