Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics

Statistical characterization of multiple-reaction monitoring mass spectrometry (MRM-MS) assays for quantitative proteomics

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<p>Abstract</p> <p>Multiple reaction monitoring mass spectrometry (MRM-MS) with stable isotope dilution (SID) is increasingly becoming a widely accepted assay for the quantification of proteins and peptides. These assays have shown great promise in relatively high throughput verifi...

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Bibliographic Details
Main Authors: Mani D R, Abbatiello Susan E, Carr Steven A
Format: Article
Language:English
Published: BMC 2012-11-01
Series:BMC Bioinformatics
Subjects:
Multiple reaction monitoring mass spectrometry (MRM-MS)
stable isotope dilution (SID)
quantification
interference detection
limits of detection and quantification
intra- and interlaboratory precision
Online Access:http://www.biomedcentral.com/1471-2105/13/S16/S9

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http://www.biomedcentral.com/1471-2105/13/S16/S9

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