Programmed cell death-ligand 2: A neglected but important target in the immune response to cancer?

Programmed cell death-ligand 2 (PD-L2) is one of the two ligands of the programmed cell death-1 (PD-1) receptor, an inhibitory protein mainly expressed on activated immune cells that is targeted in the clinic, with successful and remarkable results. The PD-1/PD-Ls axis was shown to be one of the mos...

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Bibliographic Details
Main Authors: Cinzia Solinas, Marco Aiello, Esdy Rozali, Matteo Lambertini, Karen Willard-Gallo, Edoardo Migliori
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Translational Oncology
Online Access:http://www.sciencedirect.com/science/article/pii/S193652332030303X