Effect of curcumin on the expression of NOD2 receptor and pro-inflammatory cytokines in fibroblast-like synoviocytes (FLSs) of rheumatoid arthritis (RA) patients

Effect of curcumin on the expression of NOD2 receptor and pro-inflammatory cytokines in fibroblast-like synoviocytes (FLSs) of rheumatoid arthritis (RA) patients

Abstract Background Previous studies has shown that nucleotide-binding and oligomerization domain-containing protein 2 (NOD2) is expressed in Fibroblast-like synoviocytes (FLSs) of rheumatoid arthritis (RA) patients which is stimulated by muramyl dipeptide (MDP) present in the joint environment and...

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Bibliographic Details
Main Authors: Fereshteh Akbari-Papkiadehi, Ali Akbar Saboor-Yaraghi, Elham Farhadi, Mohammad Naghi Tahmasebi, Arash Sharafat Vaziri, Leila Aghaghazvini, Marzieh Asgari, Shiva Poursani, Fatemeh Mansouri, Ahmadreza Jamshidi, Mahdi Mahmoudi
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Advances in Rheumatology
Subjects:
Curcumin
Fibroblast like synoviocytes
Inflammation
NOD2
Rheumatoid arthritis
Autoimmune disease
Online Access:https://doi.org/10.1186/s42358-023-00308-0

Internet

https://doi.org/10.1186/s42358-023-00308-0

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