Importance of the N-terminal proline for the promiscuous activity of 4-oxalocrotonate tautomerase (4-OT)
Michael addition of aldehydes to nitroolefins is an effective method to obtain useful chiral γ-nitroaldehydes. γ-Nitroaldehydes are precursors for chiral γ-aminobytiric acid analogues which have numerous pharmacological activities and are used for treatment of neurological disorders. A w...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Serbian Chemical Society
2016-01-01
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| Series: | Journal of the Serbian Chemical Society |
| Subjects: | |
| Online Access: | http://www.doiserbia.nb.rs/img/doi/0352-5139/2016/0352-51391600053L.pdf |