RNAi mediated Tiam1 gene knockdown inhibits invasion of retinoblastoma.

T lymphoma invasion and metastasis protein (Tiam1) is up-regulated in variety of cancers and its expression level is related to metastatic potential of the type of cancer. Earlier, Tiam1 was shown to be overexpressed in retinoblastoma (RB) and we hypothesized that it was involved in invasiveness of...

Full description

Bibliographic Details
Main Authors: Nithya Subramanian, Saranya Navaneethakrishnan, Jyotirmay Biswas, Rupinder K Kanwar, Jagat R Kanwar, Subramanian Krishnakumar
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3737373?pdf=render