Whole microbe arrays accurately predict interactions and overall antimicrobial activity of galectin-8 toward distinct strains of Streptococcus pneumoniae

Abstract Microbial glycan microarrays (MGMs) populated with purified microbial glycans have been used to define the specificity of host immune factors toward microbes in a high throughput manner. However, a limitation of such arrays is that glycan presentation may not fully recapitulate the natural...

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Bibliographic Details
Main Authors: Shang-Chuen Wu, Hau-Ming Jan, Mary L. Vallecillo-Zúniga, Matthew F. Rathgeber, Caleb S. Stowell, Kaleb L. Murdock, Kashyap R. Patel, Hirotomo Nakahara, Carter J. Stowell, Moon H. Nahm, Connie M. Arthur, Richard D. Cummings, Sean R. Stowell
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-27964-y