Theoretical study on the glycosidic C–C bond cleavage of 3’’-oxo-puerarin

Abstract Puerarin, daidzein C-glucoside, was known to be biotransformed to daidzein by human intestinal bacteria, which is eventually converted to (S)-equol. The metabolic pathway of puerarin to daidzein by DgpABC of Dorea sp. PUE strain was reported as puerarin (1) → 3’’-oxo-puerarin (2) → daidzein...

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Bibliographic Details
Main Authors: Jongkeun Choi, Yongho Kim, Bekir Engin Eser, Jaehong Han
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-43379-1