An NPPB Promoter Polymorphism Associated With Elevated N‐Terminal pro–B‐Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality

An NPPB Promoter Polymorphism Associated With Elevated N‐Terminal pro–B‐Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality

BackgroundElevated B‐type natriuretic peptide (BNP) levels are associated with heart failure and increased mortality in the general population. We investigated rs198389, a functional variant in the promoter region of the BNP gene (NPPB), in patients from the Atherosclerosis Risk in Communities Study...

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Bibliographic Details
Main Authors: Sara B. Seidelmann, Orly Vardeny, Brian Claggett, Bing Yu, Amil M. Shah, Christie M. Ballantyne, Elizabeth Selvin, Calum A. MacRae, Eric Boerwinkle, Scott D. Solomon
Format: Article
Language:English
Published: Wiley 2017-04-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
blood pressure
hypertension
mortality
natriuretic peptide
NPPB
N‐terminal pro–B‐type
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.116.005257

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https://www.ahajournals.org/doi/10.1161/JAHA.116.005257

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