Investigating phase separation properties of chromatin-associated proteins using gradient elution of 1,6-hexanediol

Abstract Background Chromatin-associated phase separation proteins establish various biomolecular condensates via liquid–liquid phase separation (LLPS), which regulates vital biological processes spatially and temporally. However, the widely used methods to characterize phase separation proteins are...

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Bibliographic Details
Main Authors: Peiyu Zhu, Chao Hou, Manlin Liu, Taoyu Chen, Tingting Li, Likun Wang
Format: Article
Language:English
Published: BMC 2023-08-01
Series:BMC Genomics
Subjects:
Online Access:https://doi.org/10.1186/s12864-023-09600-1