Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus

Structural characterization of a novel cyclic 2,3-diphosphoglycerate synthetase involved in extremolyte production in the archaeon Methanothermus fervidus

The enzyme cyclic di-phosphoglycerate synthetase that is involved in the production of the osmolyte cyclic 2,3-diphosphoglycerate has been studied both biochemically and structurally. Cyclic 2,3-diphosphoglycerate is found exclusively in the hyperthermophilic archaeal methanogens, such as Methanothe...

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Bibliographic Details
Main Authors: Simone A. De Rose, Michail N. Isupov, Harley L. Worthy, Christina Stracke, Nicholas J. Harmer, Bettina Siebers, Jennifer A. Littlechild, The HotSolute consortium, Christopher Bräsen, Benjamin Meyer, Simone Antonio De Rose, Jennifer Ann Littlechild, Elizaveta Bonch-Osmolovskaya, Sergey Gavrilov, Ilya Kublanov, Daniela Monti, Erica Ferrandi, Eleonora Dore, Felix Müller, Jacky Snoep
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Microbiology
Subjects:
extremolyte
cyclic 2
3-diphosphoglycerate
X-ray structure
thermophiles
synthetase
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267570/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2023.1267570/full

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